Melatonin effect on thyroid gland

Melatonin effect on the thyroid gland

Melatonin is a well-known hormone with a pronounced positive impact on human wellbeing. It is a biomarker for regulating the right sleeping-wake cycle and always offers solutions for different problems such as strong headaches. The thyroid function is positively influenced by taking melatonin, and Melatonin also affects the immune system. In short, melatonin can be a good choice everywhere when it comes to maintaining the thyroid function, maintaining the metabolism and the modulation of immune functions. You can not do without it while checking any system.

Thyroid hormone synthesis due to reactive oxygen species (ROS)

The thyroid hormones are produced by the thyroid and can be substantially divided into three groups.

- tryiodthyronin, also called T3

- Tetraiodopthyronin, also called T4 or thyroxine

- Calcitonin

These thyroid hormones are formed in the thyroid gland by reactive oxygen species. The compounds between reactive oxygen species and antioxidants are so close that the antioxidants are responsible for removing harmful reactive oxygen species (ROS) from the body cells and organs. Undoubtedly, these reactive oxygen species are essential for optimal functioning of the cells as they perform oxidative reactions in the cells.

However, when used in excess, they become dysfunctional and set the body cells under oxidative stress that can easily damage the cells. However, these reactive oxygen species also fulfill the function of thyroid hormone synthesis, which takes place in the thyroid gland. In this way, thyroid hormones are produced and serve the most important metabolic processes in the body.


How does Melatonin regulate the function of thyroid gland?


Most research deals with one aspect of the effect of melatonin on the thyroid function, namely with the role of melatonin as antioxidant. There are a number of investigations and experimental studies that deal with the effect of melatonal intake to the thyroid function. Some of them have come to the conclusion that there are specialized C cells in the thyroid, which are responsible for the production of melatonin. This is done in the context of the processing of thyroid stimulating hormone, which is mainly connected to T4 production. This clearly shows that melatonin and the thyroid stimulating hormone compensate each other.

An important aspect is that melatonin in excess block the proliferation of thyroid cells and ultimately prevent thyroid hormone synthesis. So there should be no chronic intake of melatonin, but attention to moderation.


Melatonin, thyroid and balance between sleeping and guards

The intake of melatonin proves to be helpful in coping with the symptoms of jet lag insomnia. This is a form of day sleep that disturbs the functioning of the entire day and brings weakness and problems in the daily routine. These sleep problems and fatigue faults more frequently pass with the patient with thyroid disorders. The production of thyroid stimulating hormone (TSH) and T3 depends on sleep-wax rhythm and natural light cycles.

Therefore, changes or faults of sleep behavior ultimately lead to changes in the mirror of thyroid stimulating hormones. Night coating work leads to changes in the mirror of thyroid, insulin and sex hormones, which increases the risk of autoimmune diseases. The intake of melatonin before sleeping can get the problem of irregular sleep and the mirror of thyroid stimulating hormones under control. The optimal daily dose of melatonin for this purpose is 0.5 or 5 mg. The thyroid function is improved, but the TSH values ​​associated with the correct sleeping mechanisms can be maintained alone by the one-time intake of melatonin.

The role of melatonin in hypothyroidism

An experimental study has proven that Melatonin can effectively reduce the symptoms of thyroid interfacing by acting on the pituitary thyroid system and thus eliminates the signs of fear and depression.


To the summary


Remarkable insights suggest that the intake of melatonin improves thyroid function, maintaining thyroid stimulating hormone and preventing sleep disorders that are attributable exclusively to an imbalance of the thyroid. Melatonin can effectively act as an antioxidant, and its inhibitory effect on the secretion of thyroid hormones makes it an excellent choice in the treatment of hyperthyroidism.

Some people choose melatonin preparations to solve their sleep problems, but in this case they should first consult a doctor. They should take these supplements after prescribing and in the desired amount, as it can occur in chronic intake of melatonin to obvious complications such as dizziness, nausea, anxiety and headache. In order to avoid all scenarios and enjoy a good health status, melatonin should be taken in moderation and not in excess.




Better sleep

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