Melatonin Valerian - What Is It?
Melatonin Valerian is a hormone produced by the pineal gland almost entirely in the dark. It is also proven that it is one of the elements that make up the human biological clock, i.e. it is responsible for regulating the sleep-wake rhythm.
The main function of the pineal gland is to synchronize the internal biological clock of humans with the astronomical clock, d. H. with the rhythm of light and darkness by producing melatonin in adequate quantities at a certain time day or night.
What is melatonin?
Melatonin is a neurohormone that is responsible for the regulation of sleep. This is a simple description of the meaning of melatonin to humans. It is produced in the brain by the pineal gland, a small gland in the brain, whose job it is to produce the activity of certain hormones and regulate. It may give the impression that melatonin is a sleep privilege to humans, but the truth is that it is somewhat longer exists on our planet. Melatonin is also found in bacteria, algae, fungi and even in fruits and vegetables.
Melatonin or N-acetyl-5-methoxytryptamine is a indoleamine d. H. an indole derivative containing an amino group. In the body there is formed from the amino acid tryptophan, where it is converted by an enzyme in serotonin and then in a further reaction in melatonin.
Melatonin was first isolated in 1958 from Rinderepiphysen. It was discovered by Aaron Lerner and isolated, but has long been that affects the circadian rhythm and other body processes as animal neurohormone. Subsequent research on melatonin has shown that it occurs in various organisms. It has been found that it not only affects the sleep regulation, but also has anti-inflammatory effects, improves the immune system, "fight" free radicals or alleviate the effects of jet lag and insomnia.
Melatonin: role in the body. Symptoms of a melatonin deficiency
Melatonin is a hormone produced by the pineal gland and at nightfall initiating sleep, which is why it is also called "night hormone" or "sleep hormone". In addition, it has a strong antioxidant effect and strengthens the immune system. Find out what melatonin influences and how to correct a deficiency.
Melatonin tablets - Indications For Use
Insomnia is a common affliction of travelers. They are related to the sudden change of time zone together (Jet-Lat Syndrome), and its severity depends on the direction of travel and the number of crossed time zones.
In order to alleviate the syndrome of sudden change of time zone, it is advisable to take 2 days before and during a long journey synthetic melatonin.
Melatonin supplements should blind people be administered, often complain of interference of daily sleep-wake rhythm: night to watch and work is not physiologically for our body.
People who work in shifts, often have impaired biological clock and trouble falling asleep. The administration of melatonin should relieve the symptoms and facilitate recovery.
What Causes Sleep hormone deficiency?
An abnormal amount of sleep hormones leads to the syndrome of delayed sleep phase, which often occurs in young people. In this case, the bedtime postponed by several hours because of the biological rhythm does not coincide with the limits specified by study or work rhythm.
The disorder causes drowsiness against 2 to 4 pm or only occurs in the morning at night. Even if the patient goes to bed early, he can not sleep and daytime irritable and have difficulty concentrating.
A treatment is also required at the accelerated sleep phase, which most often occurs in people over 60 years. The fault causes drowsiness before 21 clock, and in the morning you are awake and fully active until the evening hours.
Sleep, Jetlag: Is Melatonin effective?
The so-called "sleep hormone" is effective only in certain cases:
Insomnia due to a delay of the sleeping phase, in particular due to poor habits (late bedtime, use of screens ...);
Insomnia in humans over 55 years, especially if the person wakes up early;
In people who suffer from Parkinson's disease or dementia: Melatonin helps you stabilize your sleep and make your nights less restless.
Melatonin can also relieve the symptoms of a jetlag, "but only when traveling to the east with a time difference from five to ten hours. It is then taken the first two or three days between 19 and 20 o'clock local time," concludes Dr. Royant-Parola.
Melatonin is not useful in fearless insomnia or early wake up due to depression.
Melatonin for sleep support
Several studies have shown that melatonin acts sleepfeeding and a popular supplement z. B. is in insomnia. There are more effective supplements for this purpose, but the advantage is that it has fewer side effects. According to a study from 2016, Melatonin can also improve the sleep of cancer patients who suffer from insomnia. A study from 2014 shows that Melatonin is promising to relieve the effects of Jetlag and - in limited extent - insomnia. At the end of the study, the authors also concluded that the data obtained can not prove a positive effect of melatonin on the start of sleep and sleep efficiency. You do not recommend taking melatonin for shift workers. The purpose of this article is to provide unbiased opinion on melatonin, and several sources point out that it is less effective. However, that does not mean that it is with sleep problems, z. B. by air travel, can not help.